The 2nd plenary meeting of the NESTLER project was held at Synelixis premises in Athens, on the 15th and 16th of February 2023. The Consortium reviewed the progress of the project against the set objectives on all Work Packages. The members of the consortium presented the results achieved so far towards our research targets. Furthermore, preparatory actions have been taken regarding the 1st Stakeholders group meeting. In addition, during the second plenary meeting the next steps of the project were defined.